In 2008, Mibelle Biochemistry Switzerland launched an entirely new active cosmetic ingredient based on apple stem cells. In line with their motto ‘inspired by nature; realized by science’, Mibelle Biochemistry has created a basis to combine nature & science to obtain new Phyto-ingredients that were previously unavailable.

The history (old species of Swiss apple)
Fruit-growing has a long tradition in Switzerland and the use of apples as a food rich in vitamins that can be stored over the winter had great importance in the past. The storability of the apples was therefore a decisive criterion in the choice of apples grown.

At this time, the apple species ‘Uttwiler Spätlauber’ was grown in many areas as this apple was particularly suitable for storage. This was due to its high content of tannins and its long-lasting cells. Today, however, this species of apple is almost extinct. It has been replaced by more modern, optically more attractive apple species that also taste much better. Storability is no longer an issue, because nowadays fruits can be imported in the winter.

Mibelle Biochemistry has established a plant cell culture from one of the few Uttwiler Spätlauber apples from one of the few trees that still exist. Thus the valuable ingredients of this species of apple – that in principle only exists on postage stamps – are now again available to the cosmetics industry in the required quantity.

The technology (cell culture with plant-based stem cells)
After around 4 years of intensive research, Mibelle Biochemistry succeeded in cultivating plant stem cells from this apple in larger quantities. The active ingredient ‘PhytoCellTec™ Malus Domestica’ is based on these apple stem cells.

The application
Plant stem cells for the protection of skin stem cells
There are epidermal stem cells in human skin. These are effectively the ‘mother cells’ of all cells in the epidermis and are thus responsible for the formation of new cells and for the regeneration of damaged cells. As the skin is a tissue that constantly regenerates itself, the skin stem cells (epidermal stem cells) are considered to be the most important skin cells.

The efficacy
In comprehensive studies, Mibelle Biochemistry was able to demonstrate that PhytoCellTec™ Malus Domestica, the active ingredient based on apple stem cells, enhances the vitality of skin stem cells, protects their longevity and therefore delays skin aging.

The use of plant stem cells to protect skin stem cells is patent pending by Mibelle Biochemistry.

Summary
PhytoCellTec™ Malus Domestica offers entirely new opportunities in cosmetics. By using plant stem cells to protect skin stem cells skin chronological and environmental induced skin aging can be delayed. PhytoCellTec™ Malus Domestica maintains the power of regeneration for a young and vital looking skin. In a recent edition of US Vogue it was revealed that even Michelle Obama is a fan of this ingredient.

Visit www.mibellebiochemistry.com for further details about PhytoCellTec™ Malus Domestica.

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